Treatments

Antihistamines for Eczema

How Antihistamines Help

While antihistamines don't treat eczema directly, they can help:

  • Reduce itching sensation
  • Help you sleep better during flare-ups
  • Manage allergic triggers that might worsen eczema
Non-Drowsy Options

Fexofenadine (Recommended)

  • Most effective non-drowsy option
  • Can be taken during the day
  • Particularly good for daytime itch relief
  • Available over the counter

Other Non-Drowsy Options:

  • Cetirizine (can cause drowsiness in some people)
  • Loratadine
Sedating Options

These can be helpful for nighttime use when itching disrupts sleep:

  • Chlorphenamine (Piriton)
  • Hydroxyzine
  • Promethazine

Important Note

Sedating antihistamines can affect your ability to drive or operate machinery. Only take these before bed.

Usage Guidelines

Best Practices:

  • Take regularly during flare-ups rather than as needed
  • Consider using non-drowsy options during the day and sedating ones at night
  • Discuss long-term use with your healthcare provider
  • Different antihistamines work better for different people - you may need to try a few to find what works best

When to See Your Doctor

  • If over-the-counter antihistamines aren't helping
  • If you need to use them for extended periods
  • If you experience any side effects